The conventional analysis of variance applied to designs in which each subject is measured repeatedly requires stringent assumptions regarding the variance-covariance (i. e., correlations among ...

This paper describes a general method for deriving optimal procedures for problems where the covariance matrices are patterned under both null and alternative hypotheses. The pattern considered in ...

Given the drawbacks of implementing multivariate analysis for mapping multiple traits in genome-wide association study (GWAS), principal component analysis (PCA) has been widely used to generate ...