The new protocol automates the sample preparation steps (cleansing and desalting) of peptides designated for mass spectrometry and the subsequent spotting onto a MALDI target plate using the Agilent ...

Dice each gel slice into small pieces (1 mm2, or crush with razor blade) and place into 0.65 mL tubes. Add ~50 µL (or enough to cover) of 25 mM NH4HCO3/50% ACN, vortex and mix on the Nutator for 30 ...

Though unglamorous, sample prep is widely regarded as the most critical step in performing robust mass spectrometry. Any number of problems—contamination, incomplete digestion, unwanted side reactions ...

(RTTNews) - Becton, Dickinson and Company (BDX) has received 510(k) clearance from the FDA for the BD Kiestra IdentifA system, which is designed to automate the preparation of microbiology bacterial ...

Sample preparation for mass spectrometry has been the topic of several recent symposia extensively covered in the pages of GEN. Mass spectrometry has grown over the years into an essential tool for ...

MALDI imaging — an analytical technique that detects potential biomarkers directly from tissue sections — has become popular over the last 10 years. One significant aspect is the development protocols ...

Using MALDI-TOF, researchers can quickly and accurately determine polymer, protein and nucleic acid masses. They can also analyze and resolve complex assortments of smaller peptides and ...