Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

The Stepped Wedge Cluster Randomized Trial is a research methodology that has been growing in popularity, particularly for pragmatic implementation and dissemination trials. SW-CRTs can have ...

Surrogate decision makers for incapacitated, critically ill patients often struggle with decisions related to goals of care. Such decisions cause psychological distress in surrogates and may lead to ...

In an open-label, two-period, two-sequence, cross-sectional, cluster-randomized, crossover trial, we assigned hospitals in Ontario, Canada, to use either lactated Ringer’s solution or normal saline ...