A machine-learning model computationally breaks down how segments of amino acid chains determine a protein's function, which could help researchers design and test new proteins for drug development or ...

Amino acids are the basic building blocks of living organisms and typically occur in a configuration known as the L-form. However, there are a few exceptional examples of the structural mirror image ...

With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and structure-regulating amino acids can be determined much more precisely than ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

Mutations can occur on several levels, including genetic, but can also take the form of amino acid replacements during protein synthesis. Amino acid replacements can be deleterious, neutral, or ...

5-hydroxytryptophan (5-HTP) is a naturally occurring amino acid and the essential precursors of serotonin (5-hydroxytryptamine) an important neurotransmitter for mood regulation, memory, learning, and ...